A Smart Investment: The Health, Education, and Economic Returns of Malaria Chemoprevention in School-Aged Children Across Ten High-Burden Countries

This study demonstrates that malaria chemoprevention for school-aged children across ten high-burden sub-Saharan African countries is a highly cost-effective investment, generating substantial societal net benefits through improved health, reduced school absenteeism, and enhanced educational outcomes, with benefit-cost ratios ranging from 3.71 to 39.5.

Snyman, K., Angrist, N., Cohee, L. M., Worrall, E.2026-03-25📄 health economics

Does the Health System Model Shape Prevention? Evidence from 22 OECD Countries (2004-2023)

This study analyzing 22 OECD countries from 2004 to 2023 finds that the share of health expenditure allocated to prevention is largely independent of a healthcare system's structural organization (financing and provision), suggesting that investment in prevention is driven more by external political and strategic factors than by the system's inherent design.

Marraffa, P., Marega, L., Politano, G., Gianino, M. M.2026-03-23📄 health economics

Building a Resilient Antibiotic Market: India Sets the Pace An econometric modelling approach to estimate revenues in Indian private markets for a novel, broad-spectrum intravenous antibiotic

This paper employs econometric modeling to demonstrate that India, facing a severe antibiotic resistance crisis, can pioneer the market entry and financial viability of novel broad-spectrum intravenous antibiotics through innovative revenue strategies, thereby transforming the country into a global hub for antibiotic innovation and health security.

Maitreyi, L., Rajagopal, S., Anandkumar, A., Datta, S.2026-03-22📄 health economics

Catastrophic Health Expenditure Among Gastrointestinal Cancer Patients Undergoing Surgery in Uganda: A Prospective Study

This prospective study in Uganda reveals that over 60% of gastrointestinal cancer patients undergoing surgery face catastrophic health expenditure, with the poorest households and women most severely affected by asset depletion and financial insecurity due to the absence of national health insurance.

Akello, V. V., Atieno, C., Asiimwe, L., Kurigamba, G. K., Nakafeero, M., Nkangi, K., Kamugisha, D., Vickos, U., Jombwe, J., Waako, R., Byanyima, R.2026-03-19📄 health economics

The Economic Burden of KCNT1-Related Disorders in the United States: Insights from Caregiver-Reported and EMR-Derived Data

This study quantifies the substantial economic burden of KCNT1-related disorders in the United States by combining caregiver-reported and electronic medical record data, revealing that annual costs per family range from approximately $355,000 to nearly $800,000 and are driven primarily by hospitalizations and caregiving-related income loss, thereby underscoring the urgent need for targeted therapies and systemic policy support.

Abuhl, A., Bryan, B. A., Wright, M., Rosenberg, A., West, J., Drislane, S.2026-03-17📄 health economics

Cost-effectiveness of end-game strategies against sleeping sickness across the Democratic Republic of Congo

This study models the cost-effectiveness of various end-game strategies in the Democratic Republic of Congo, finding that while front-loaded investments are required to achieve elimination of transmission by 2030 in most health zones, such ambitious efforts would significantly reduce mortality and prove cost-effective compared to the status quo.

Antillon, M., Huang, C.-I., Sutherland, S. A., Crump, R. E., Brown, P. E., Bessel, P. R., Crowley, E. H., Snijders, R., Hope, A., Tirados, I., Dunkley, S., Verle, P., Lebuki, J., Shampa, C., Mwamba Mi (…)2026-03-16📄 health economics

Bayesian Joint Longitudinal-Survival Modeling of Functional Recovery Trajectories and Time to Independent Community Ambulation Following Robotic Exoskeleton-Assisted Stroke Rehabilitation: A Multi-Centre Cohort Study in Canada

This multi-centre Canadian cohort study utilized a Bayesian joint modelling framework to demonstrate that both the current level and the rate of improvement in lower-extremity motor function are independently predictive of achieving independent community ambulation following robotic exoskeleton-assisted stroke rehabilitation, thereby supporting dynamic, trajectory-based treatment planning.

Lim, A., Desai, P.2026-03-16📄 health economics

Economic analysis of a school-based menstrual health intervention (MENISCUS) among female adolescents in Uganda

This study provides the first economic analysis of scaling a school-based menstrual health intervention (MENISCUS) in Uganda, estimating national implementation costs and demonstrating economies of scale to inform government investment and policy decisions.

Lagony, S., Bucci, D., Dwommoh, R. A. K., Mugenyi, L., Nelson, K. A., Obicho, E., Matovu, F., Nakalema, S., Weiss, H. A., Greco, G.2026-03-13📄 health economics

Resource need and cost estimates for universal health coverage across 122 countries using the WHO UHC Compendium

This study utilizes a new ingredient-based costing model aligned with the WHO UHC Compendium to estimate that achieving 80% coverage of essential health interventions across 122 low- and middle-income countries would require an annual investment of USD 2.0 trillion, providing a transparent and practical framework for national health planning.

Nederpelt, C., Abou Jaoude, G., Surgey, G., Isaeva, B., Zhetibaeva, S., Htat, H. W., Haghparast-Bidgoli, H., Baltussen, R.2026-03-13📄 health economics